Synthesis, characterization and antioxidant activities of novel N-substituted pyrazoline derivatives bearing 3-benzo[b]thiophene and 5-styryl substituents
By: Krishnan, Radhakrishnan
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Contributor(s): Pandy, Karthik Manikandan.
Publisher: New Delhi CSIR 2022Edition: Vol.61(7), Jul.Description: 703-716p.Subject(s): GENERAL CHEMISTRYOnline resources: Click here
In:
Indian journal of chemistry (Section B)Summary: The new series of N-substituted pyrazoline derivatives bearing benzo[b]thiophene and styryl with trifluoromethyl substitution at para- and meta- positions were synthesized. The structures of newly synthesized compounds were characterized by UV, IR, NMR, Mass and single crystal XRD (SCXRD) and had been screened for antioxidant activity. The in vitro antioxidant activities screening revealed that hydroxyl radical scavenging (HRS) activities of compounds 3c, 3f, 4a, 4e, 4f, 5c, 5d 5e and 5g are stronger than the other compounds and the compound 5g shows much better antioxidant activity.
| Item type | Current location | Call number | Status | Date due | Barcode | Item holds |
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Articles Abstract Database
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School of Pharmacy Archieval Section | Not for loan | 2023-0776 |
The new series of N-substituted pyrazoline derivatives bearing benzo[b]thiophene and styryl with trifluoromethyl substitution at para- and meta- positions were synthesized. The structures of newly synthesized compounds were characterized by UV, IR, NMR, Mass and single crystal XRD (SCXRD) and had been screened for antioxidant activity. The in vitro antioxidant activities screening revealed that hydroxyl radical scavenging (HRS) activities of compounds 3c, 3f, 4a, 4e, 4f, 5c, 5d 5e and 5g are stronger than the other compounds and the compound 5g shows much better antioxidant activity.
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